Drunk Elephant Protini Polypeptide Cream jar
Drunk Elephant

Protini Polypeptide Cream

Moisturizer 50 ml
9.6OUT OF 10
Great formula

Formula has a high safety profile. Suitable for most skin types.

56
Safe
1
Caution
0
Higher risk

Score breakdown

Safety10/10
Barrier support10/10
Acne-safe8.4/10
Active treatment8.2/10

Our verdict

Protini lists nine distinct peptides, which is genuinely more than most 'peptide cream' marketing delivers — signal peptides like palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1 (the Matrixyl family) sit alongside several growth-factor-mimicking oligopeptides and a copper peptide, all before the ninth amino acid in the list even shows up. That's a real, varied peptide complex rather than a single token ingredient. Where the formula pulls back is concentration disclosure: like almost every peptide product on the market, exact percentages aren't published, and effective peptide concentrations are typically measured in parts per million, so 'nine peptides' tells you about variety, not necessarily potency. The cream itself is a genuinely pleasant, mousse-like moisturizer built on glycerin, ceramide-adjacent fatty acids (linoleic, linolenic) and sodium hyaluronate for hydration, plus a full amino acid panel that functions as a secondary humectant system. It's fragrance-free in the traditional sense but does contain phenylpropanol, a fragrance-adjacent ingredient with a mild scent, worth knowing if you're strictly fragrance-avoidant. The honest expectation: this is a well-built, multi-peptide moisturizer for gradual, supportive anti-aging use over months, not a fast-acting treatment — a good complement to retinol or vitamin C rather than a replacement for either.

At a glance

What it does
hydrationsoothingbarrier supportanti-aging
Best for
sensitive skindry and dehydrated skinmost skin types
Not enough for
visible hyperpigmentation

Key ingredients

Full ingredient list (58)

Colour indicates our safety assessment for each ingredient — green is well-tolerated, amber warrants caution, red is higher-risk. Tap any ingredient to read its full profile.

Frequently asked

Does Protini really contain nine peptides?
Yes, the ingredient list includes nine distinct peptide types — signal peptides like palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1, several oligopeptides, and a copper peptide — which is a genuinely varied complex compared to most single-peptide moisturizers on the market.
How strong are the peptides in this cream?
The exact concentrations aren't published, which is standard for peptide products, since effective doses are typically measured in parts per million. The variety of peptides here is real, but 'nine peptides' describes the formula's breadth rather than confirming a clinically potent dose of each one.
Is Drunk Elephant Protini fragrance-free?
It doesn't contain added fragrance in the traditional sense, but it does include phenylpropanol, an ingredient with a mild inherent scent that's sometimes used as a preservative booster. If you're strictly avoiding all aromatic ingredients, it's worth knowing this is present.
What is the score based on?
The score comes from the same Pure Moonlight ingredient analyzer used across the whole site. It weighs safety, barrier support, acne and comedogenic risk, and active-ingredient strength, so this product's score is directly comparable to any ingredient page here.

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