Retinoid

Tretinoin

The gold standard prescription retinoid — the most clinically proven ingredient for anti-aging, acne, and skin texture improvement.

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⚠ Use with Caution

Comedogenic Rating

0/5

Irritation Potential

2/5

What is it?

Tretinoin is the acid form of vitamin A (retinoic acid). Unlike retinol, it does not require conversion in the skin — it binds directly to retinoid receptors (RAR), making it significantly more potent. It is available only by prescription in most countries.

Used to treat acne, reduce fine lines and wrinkles, improve skin texture, fade hyperpigmentation, and accelerate cell turnover. It is the most evidence-backed topical for photoaged skin.

Key Benefits

✦

Collagen stimulation

Directly stimulates fibroblasts to produce new collagen, reducing wrinkles and improving firmness.

◈

Accelerates cell renewal

Speeds up skin cell turnover, clearing acne, smoothing texture, and fading dark spots faster.

✧

Reduces hyperpigmentation

Proven to fade melasma, sun spots, and post-inflammatory hyperpigmentation.

Suitable for

acne-prone skinaging skinskin with hyperpigmentationskin with uneven texture

Main Actions

✓ collagen stimulation✓ cell renewal✓ hyperpigmentation reduction✓ acne treatment✓ skin resurfacing

Important considerations

Tretinoin requires a prescription and must be introduced slowly (start 2–3x per week) to avoid irritation, dryness, and peeling. Mandatory daily SPF use is essential. Not safe during pregnancy.

Frequently Asked Questions

What does Tretinoin do for skin?

Used to treat acne, reduce fine lines and wrinkles, improve skin texture, fade hyperpigmentation, and accelerate cell turnover. It is the most evidence-backed topical for photoaged skin.

Who should use Tretinoin?

Tretinoin is suitable for: acne-prone skin, aging skin, skin with hyperpigmentation, skin with uneven texture.

Are there any warnings about Tretinoin?

Tretinoin requires a prescription and must be introduced slowly (start 2–3x per week) to avoid irritation, dryness, and peeling. Mandatory daily SPF use is essential. Not safe during pregnancy.

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