Antioxidant

Resveratrol

The antioxidant of red wine — resveratrol activates sirtuins (longevity genes), protects DNA from damage, and neutralizes free radicals. One of the most powerful polyphenolic antioxidants with proven anti-aging effects.

Antioxidantsirtuinanti-agingDNA protection

✓ Safe

Comedogenic Rating

0/5

Irritation Potential

0/5

What is it?

Resveratrol (3,5,4'-trihydroxystilbene) — a stilbene polyphenol synthesized by plants in response to stress (UV, pathogens, drought). Main sources: skin of red grapes, Japanese knotweed (Polygonum cuspidatum), peanuts. Main forms: trans-resveratrol (active) and cis-resveratrol. Key property: SIRT1 activator — sirtuin-1 is an NAD+-dependent deacetylase associated with cellular longevity and DNA repair.

Antioxidant serums and anti-aging products. Effective in concentrations of 0.1–1%. Combines with vitamin C, E, and ferulic acid for synergistic antioxidant protection. Unstable in light — best in opaque packaging.

Key Benefits

✦

Activation of SIRT1 and DNA protection

SIRT1 (sirtuin-1) is activated by resveratrol and regulates the response to DNA damage, inflammation, and stress. Increased SIRT1 activity improves DNA repair, reduces cellular aging (senescence), and inflammation. An effect absent in most antioxidants — a unique 'gene' action.

◈

Powerful antioxidant protection against UV and ROS. Trans-resveratrol neutralizes superoxide anion, hydroxyl, and peroxyl radicals. ORAC higher than most polyphenols. Reduces UV-induced activation of MMP-1 — protects collagen. When combined with vitamins C and E — synergistic antioxidant effect.

✧

Tone brightening and regulation of melanogenesis

Resveratrol inhibits tyrosinase and TRP-1 (tyrosinase-related protein-1) — key enzymes in melanin synthesis. Clinical studies: 4-week application of a formula with 1% resveratrol — significant brightening of pigmented spots. The effect is comparable to arbutin with higher antioxidant activity.

Suitable for

Mature skinDull skinNormal skin

Main Actions

✓ Antioxidant protection✓ Activation of longevity genes (SIRT1)✓ Tone brightening

Trans- vs Cis-Resveratrol

Trans-resveratrol — biologically active form (stable configuration). Cis-resveratrol — less active isomeric form. Quality products contain trans-resveratrol. Unstable in UV and alkaline environments — store in a dark place and check the shade: if it darkens — partial oxidation.

CategoryAntioxidants

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