Humectant

Polyglutamic Acid

A moisturizer that surpasses hyaluronic acid — polyglutamic acid retains 5000 times more moisture and simultaneously strengthens the skin's own synthesis of hyaluronic acid. A trend from Asian cosmetics that is conquering the entire market.

HydrationPGAHA enhancerBarrier
✓ Safe
Comedogenic Rating
0/5
Irritation Potential
0/5

What is it?

Polyglutamic Acid (γ-PGA) — a natural polymer of glutamic acid synthesized by the bacterium Bacillus subtilis natto during soy fermentation (natto). The molecular weight varies from 100 kDa to 2000 kDa. Water-soluble, forms viscous gels. Retains up to 5000 times its own weight in water — for comparison, HA retains ~1000. Especially popular in Korean and Japanese cosmetics.

A premium moisturizer in serums and essences. Effectively combines with hyaluronic acid as an enhancer. Important for mature and dehydrated skin, where the natural production of HA is reduced.

Key Benefits

Super powerful hydration — 5000 times more than HA
Due to its polymer structure with many hydrophilic carboxyl groups, PGA retains significantly more water than HA. The surface film prevents moisture evaporation, while the smaller fraction of PGA penetrates the stratum corneum, hydrating from within.
Stimulation of the skin's own synthesis of hyaluronic acid
PGA inhibits hyaluronidase — the enzyme that breaks down HA in the skin. The result: the skin's own HA breaks down more slowly, and its content in the skin increases. This is a "boosting" effect that is absent in HA itself.
Strengthening the barrier and protection against aging
Stimulates the synthesis of filaggrin and other structural proteins of the stratum corneum. Improves barrier integrity, reduces TEWL. Regular use reduces the depth of dehydration lines and fine wrinkles.

Suitable for

Dehydrated skinMature skinNormal skinSensitive skin

Main Actions

✓ Powerful hydration✓ Stimulation of HA synthesis✓ Strengthening the barrier
PGA + HA = synergy

Polyglutamic acid and hyaluronic acid combine excellently. PGA acts on the surface (moisture retention and protection from evaporation), HMW HA — at the level of the stratum corneum, LMW HA — deeper. Together they provide hydration at all levels. That is why many premium serums contain both ingredients.

Check if this ingredient works for your skin — analyze your full product formula for free.

Analyze your product