Peptide

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine

A specialized signal peptide (also known as Filaggrin) used in barrier-repair formulas to support a more resilient-looking skin surface.

peptidebarrier supportanti-aging
✓ Safe
Comedogenic Rating
0/5
Irritation Potential
0/5

What is it?

Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine (commonly marketed as Filaggrin or Filladerm) is a synthetic peptide studied for supporting the skin's natural barrier protein production processes.

Used in barrier-repair and anti-aging serums to support a more resilient, hydrated-looking skin surface.

Key Benefits

Barrier support
Studied for supporting the skin's natural barrier function.
Anti-aging positioning
Often included in formulas targeting overall skin resilience and texture.

Suitable for

mature and dry skinskin with barrier concerns

Main Actions

✓ barrier support✓ anti-aging
When it may be insufficient

As with most cosmetic peptides, real-world topical penetration and effect size are modest compared to in-vitro study claims.

Frequently Asked Questions

What does Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine do for skin?
Used in barrier-repair and anti-aging serums to support a more resilient, hydrated-looking skin surface.
Who should use Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine?
Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine is suitable for: mature and dry skin, skin with barrier concerns.
Are there any warnings about Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine?
As with most cosmetic peptides, real-world topical penetration and effect size are modest compared to in-vitro study claims.

Check if this ingredient works for your skin — analyze your full product formula for free.

Analyze your product