Emollient

Isopropyl Palmitate

Isopropyl Palmitate is a light synthetic emollient with a dry texture. It provides products with a "powdery dry" feel and facilitates application. One of the most common conditioning emollients in mass-market cosmetics.

Light emollientdry-touchPalmitate esterSkin conditioner
✕ High Risk
Comedogenic Rating
3/5
Irritation Potential
1/5

What is it?

Isopropyl Palmitate (IPP) — an ester of palmitic acid (C16) and isopropanol. Molecular weight ~298 Da. A colorless liquid with minimal odor. Low viscosity, spreads well. Structurally similar to Isopropyl Myristate (IPM, C14), but with a longer chain → slightly greasier feel. Both belong to the class of 'isopropyl esters' in cosmetics. May have comedogenic effects on acne-prone skin (rating ~4/5 on some scales) — an important feature often noted in the context of acne-prone formulations. Widely available, relatively inexpensive.

Light day creams and body lotions, makeup bases and primers, SPF products for normal and combination skin, hair products (conditioners).

Key Benefits

Dry, powdery feel — lightness without a greasy film
Isopropyl Palmitate provides a characteristic 'dry-touch' feel upon application: spreads in a thin layer, absorbs quickly, and leaves no visible greasy residue. Popular in mass-market creams and body lotions precisely because of this light texture. Compared to mineral oil (occlusive, greasy) or plant oils (which can be heavy) — IPP gives a more 'clean' feel on the skin.
Improvement of spreadability and appearance of the formula
IPP reduces the viscosity of thick components in the formula and improves how the cream or lotion spreads on the skin. A few percent of IPP in the formula — and the product applies more evenly, with less drag. In primers and foundations: improves smooth application with a brush or sponge. Often used as part of an "emollient blend" along with cyclomethicone or dimethicone.
Enhancement of active ingredient penetration
Isopropyl esters (IPM, IPP) are known as penetration enhancers — they facilitate the delivery of actives through the stratum corneum. Mechanism: they interact with the lipids of the stratum corneum, temporarily increasing its permeability. Useful in formulations with AHA, BHA, retinol: IPP not only provides a pleasant texture but also helps actives penetrate better. Important: this effect also increases potential irritation — it should be considered when developing formulations for sensitive skin.

Suitable for

Normal and oily skinLight texturesBody and hair

Main Actions

✓ Light dry-touch emollient✓ Improvement of spreadability✓ penetration enhancer
IPP and comedogenicity — facts and myths

Isopropyl Palmitate often appears in 'comedogenic ingredients' lists with a score of 4/5. These scales are based on the rabbit ear model from the 1970s-80s — the method is criticized for its irrelevance to humans. There is insufficient clinical research confirming the mass comedogenicity of IPP in cosmetic concentrations. However, for acne-prone skin: if you notice breakouts from products with IPP/IPM — it's better to avoid. For normal/dry/mature skin — IPP is a safe choice.

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