Home / EncyclopediaProducts / Glabridin
Isoflavanone

Glabridin

The most active brightening compound in licorice root extract, with potent tyrosinase-inhibiting and anti-inflammatory properties.

brighteninglicoricetyrosinase inhibitoranti-inflammatory
⚠ Unknown
Comedogenic Rating
0/5
Irritation Potential
0/5

What is it?

Glabridin is an isoflavan extracted from the root of Glycyrrhiza glabra. It inhibits tyrosinase, the key enzyme in melanin biosynthesis, and also suppresses UVB-induced inflammatory responses that trigger post-inflammatory hyperpigmentation.

Used in brightening serums and creams to reduce dark spots, melasma, and hyperpigmentation through tyrosinase inhibition — a natural alternative to hydroquinone.

Key Benefits

✦
Potent tyrosinase inhibitor
Among the most effective natural tyrosinase inhibitors, reducing melanin production significantly.
◈
Prevents UV-induced pigmentation
Helps prevent hyperpigmentation triggered by UV exposure.
✧
Anti-inflammatory
Reduces post-inflammatory hyperpigmentation by calming skin inflammation.

Suitable for

skin with hyperpigmentationuneven skin tonesensitive skinall skin types

Main Actions

✓ tyrosinase inhibition✓ brightening✓ anti-inflammatory✓ hyperpigmentation prevention
When it may be insufficient

Glabridin has limited stability in formulas — it degrades with light and air exposure. Look for it in opaque, airtight packaging. Always combine with SPF for maximum efficacy.

Frequently Asked Questions

What does Glabridin do for skin?
Used in brightening serums and creams to reduce dark spots, melasma, and hyperpigmentation through tyrosinase inhibition — a natural alternative to hydroquinone.
Who should use Glabridin?
Glabridin is suitable for: skin with hyperpigmentation, uneven skin tone, sensitive skin, all skin types.
Are there any warnings about Glabridin?
Glabridin has limited stability in formulas — it degrades with light and air exposure. Look for it in opaque, airtight packaging. Always combine with SPF for maximum efficacy.

Check if this ingredient works for your skin — analyze your full product formula for free.

Analyze your product