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Brightening Agent

Deoxyarbutin

A synthetic brightening ingredient considered more potent than arbutin, used to reduce hyperpigmentation and even skin tone.

brighteninghyperpigmentationtyrosinase inhibitoradvanced
⚠ Unknown
Comedogenic Rating
0/5
Irritation Potential
0/5

What is it?

Deoxyarbutin (4-[(tetrahydro-2H-pyran-2-yl)oxy]phenol) is a synthetic compound designed to deliver arbutin's melanin-inhibiting activity more potently. Unlike arbutin, it does not require hydrolysis to release hydroquinone — it inhibits tyrosinase directly and selectively.

Used in targeted brightening serums and dark spot treatments for hyperpigmentation, melasma, sun spots, and post-inflammatory marks.

Key Benefits

✦
Potent tyrosinase inhibition
Inhibits tyrosinase more effectively than standard arbutin at equivalent concentrations.
◈
Hyperpigmentation reduction
Clinically shown to reduce the appearance of dark spots and uneven pigmentation.
✧
No hydroquinone conversion
Inhibits melanin directly without generating free hydroquinone as a byproduct.

Suitable for

skin with hyperpigmentationuneven skin toneskin with dark spotsmelasma

Main Actions

✓ tyrosinase inhibition✓ brightening✓ hyperpigmentation reduction
When it may be insufficient

Deoxyarbutin should be combined with daily broad-spectrum SPF to prevent re-pigmentation. Patch test recommended as some individuals may experience mild irritation.

Frequently Asked Questions

What does Deoxyarbutin do for skin?
Used in targeted brightening serums and dark spot treatments for hyperpigmentation, melasma, sun spots, and post-inflammatory marks.
Who should use Deoxyarbutin?
Deoxyarbutin is suitable for: skin with hyperpigmentation, uneven skin tone, skin with dark spots, melasma.
Are there any warnings about Deoxyarbutin?
Deoxyarbutin should be combined with daily broad-spectrum SPF to prevent re-pigmentation. Patch test recommended as some individuals may experience mild irritation.

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