Emollient

Acetyl Tetrapeptide-9

Laminin-stimulator for the dermo-epidermal junction — acetyl tetrapeptide-9 restores the "glue" between the epidermis and dermis, increases tone and lifting effect. One of the few peptides focused on the basement membrane.

lamininbasement membraneliftingtone

✓ Safe

Comedogenic Rating

0/5

Irritation Potential

0/5

What is it?

Acetyl Tetrapeptide-9 — an acetylated tetrapeptide (LNKL or other sequence depending on the manufacturer). Target action: basement membrane of the dermo-epidermal junction. Stimulates the synthesis of laminin-5 (laminin-332) — the main anchoring protein of hemidesmosomes — and collagen XVII, which retains basal keratinocytes. Weakening of the basement membrane is a mechanism of sagging and loss of tone with aging.

Lifting serums and products against skin sagging. Especially effective for the skin of the face and neck. Combines with hexapeptide-11, palmitoyl tripeptide-5 for synergy at the level of different matrix structures.

Key Benefits

✦

Stimulation of laminin-5 and strengthening of the basement membrane

Laminin-5 (laminin-332) — a key anchoring protein that holds the epidermis on the dermis through hemidesmosomes. Acetyl tetrapeptide-9 increases the expression of laminin-332 in basal layer keratinocytes. Clinical data: 40% increase in laminin-332 synthesis in vitro.

◈

Lifting effect and increase in skin tone

Restoration of the basement membrane improves adhesion between skin layers — mechanical "support" of contours. The skin becomes firmer, looks lifted. In clinical studies: after 4 weeks — reduction of sagging and improvement of facial oval as assessed by panelists.

✧

Protection against fragmentation of the basement membrane

UV and free radicals destroy the basement membrane through the activation of laminin-degrading proteases. Acetyl tetrapeptide-9 increases the resistance of the basement membrane to degradation. Combination with antioxidants (vitamin C, E, astaxanthin) enhances protection.

Suitable for

mature skinsagging skinnormal skin

Main Actions

✓ restoration of the basement membrane✓ lifting effect✓ increase in tone

Hexapeptide-11 vs Acetyl Tetrapeptide-9

Both affect the basement membrane, but somewhat differently. Hexapeptide-11 (Filmexel) — stimulates laminin-5 and accelerates cell renewal through yeast peptide. Acetyl tetrapeptide-9 — more specific to laminin-332 and collagen XVII through synthetic acetylated peptide. The combination of both in one formula — synergistic effect on the basement membrane.

CategoryEmollients

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