Emollient

Acetyl Tetrapeptide-5

Eyeseryl — the most studied peptide against puffiness and dark circles under the eyes. Reduces capillary permeability, increases skin elasticity, and decreases swelling. Clinically proven: -70% puffiness under the eyes in 28 days.

Eyeseryleye puffinessdark circlesperiorbital area
✓ Safe
Comedogenic Rating
0/5
Irritation Potential
0/5

What is it?

Eyeseryl — acetyl-HETK (His-Glu-Thr-Lys) tetrapeptide. Mechanism of action: reduces the permeability of blood and lymphatic capillaries in the periorbital area → less fluid and protein leakage into the intercellular space → reduction of swelling. Additionally stimulates the synthesis of elastin and HA to increase the firmness of the thin skin around the eyes. INCI: Acetyl Tetrapeptide-5. Effective concentration: 3–5 ppm. Clinical studies: -70% swelling in 28 days, -65% bags under the eyes.

Specialized products for the skin around the eyes: serums and creams against puffiness, dark circles, and bags. One of the standard peptides in eye-care formulas.

Key Benefits

Reduction of swelling and bags under the eyes (-70% in 28 days)
Acetyl Tetrapeptide-5 reduces capillary permeability in the periorbital area — a key mechanism for the formation of puffiness. Clinical study by Lipotec (n=20): 3 ppm in eye cream-gel, 28 days — reduction of swelling by 70% and bags under the eyes by 65% compared to baseline. The result is noticeable after just 1–2 weeks of regular use.
Correction of dark circles through reduced microvascular permeability
Dark circles are formed due to the leakage of hemoglobin and its breakdown in the thin skin around the eyes. Reduced vascular permeability of Eyeseryl → less hemoglobin leakage → reduction of the blue-maroon tint. The effect is enhanced when combined with vitamin K and caffeine (vasoconstriction).
Restoration of elasticity in the thin periorbital skin
Eyeseryl stimulates the synthesis of elastin and HA in the fibroblasts of the periorbital area. The thin skin around the eyes is the first to show loss of firmness. Increased elastin levels → less pronounced "crow's feet" and overall tightening of the area. Synergistic action with retinol and peptides (palmitoyl tripeptide-1) in complex eye-care formulas.

Suitable for

skin with puffiness under the eyesskin with dark circlesmature skin

Main Actions

✓ reduction of puffiness (vascular permeability)✓ correction of dark circles✓ increase in elasticity
Eye-care peptide complex

Eyeseryl (reduction of swelling) + Argireline (expression wrinkles) + Leuphasyl (synergist of Argireline) + Haloxyl (dark circles from hemoglobin) = complete eye-care peptide complex. Each peptide targets a different aging mechanism in the eye area. The most effective eye serums contain at least 2–3 peptides from this list. Concentration of each: 3–5 ppm.

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